According to a study of 150 senior executives conducted by OfficeTeam, 47% said a single resume typo is enough to remove someone from consideration.
Waddya think? Seems a little rough to me, although I suppose it would depend on the job--and on the typo. If they spelled my name wrong, I would probably overlook it (since approximately 47% of people that send me e-mails make that mistake). But if I was hiring a secretary and the resume misspelled "business" or something similar, it would raise my eyebrow. Still, I would give the person a chance if their qualifications looked stellar.